Sultopride hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Sultopride Hydrochloride 是一种选择性多巴胺 D2 和 D3 受体拮抗剂。

Sultopride Hydrochloride is a selective dopamine D2 and D3 receptor antagonist.

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Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride hydrochloride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride hydrochloride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05).

LIN-1418 hydrochloride

GPCR/G Protein

Dopamine Receptor

Dopamine

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23694-17-9

390.93

C17H27ClN2O4S

>98% (HPLC)

DMSO:50 mg/mL (127.90 mM)

Cl.CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(=O)(=O)CC

N-((1-Ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide hydrochloride

(-20℃)

With Ice Pack

≥ 2 years